Synthesis, Characterization, Anti-bacterial and Anti-inflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole

Bismuth, known as a heavy metal, is excluded from this class due to its low toxicity. Due feature, bismuth containing compounds have always been interesting in the field of medicinal chemistry. For reason, discovery new and investigation their biological properties are very important for field. In study, three bismuth(III) formulated [Bi(L)2X3] (L: 5-chloro-2-mercaptobenzothiazole (ClMBZT); X: Cl, Br, I) were synthesized first time and, molecular structure them elucidated by series spectroscopic techniques. Thermal stability degradation steps title analyzed Thermogravimetric-Differential Analysis (TG-DTA). The antibacterial study has conducted against six strains bacteria, results indicated that generally showed more effective activity than free ligand. anti-inflammatory potential was investigated through vitro lipoxygenase enzyme inhibition studies. show higher